Heart attack occurs when blood stops flowing properly to a part of the heart, the heart muscle is injured because it is not receiving enough oxygen. This usually happens because one of the coronary arteries that supplies blood to the heart develops a blockage due to an unstable buildup of white blood cells, fat and cholesterol.

A recent study of the World Health Organization has shown that cardiovascular disease is the first cause of death . Furthermore the heart strokes are the most preventable death globally. Indeed, efforts to improve lifestyles, controlling lifestyle-related major cardiovascular risk factors, will definitely contribute to cardiovascular disease prevention.

In the past, a general consensus existed for the clinical syndrome designated as Myocardial Infarction (MI). In studies of disease prevalence, the World Health Organizarion (WHO) defined Myocardial Infarction from symptoms, ECF abnormalities and cardiac enzymes. However, the development of ever more sensitive and myocardial tissue-specific cardiac biomarkers and more sensitive imaging techniques now allows for detection of very small amounts of myorcardial injury or necrosis. Electrocardiographic ECG findings, elevated values of biochemical markers (biomarkers) of myocardial necrosis, and imaging that will help doctor to recognized myocardial infarction.

Heart attack may be the first manifestation of coronary artery disease (CAD) or it may occur, repeatedly, in patients with established disease. The term myocardial infraction may have major psychological and legal implications for the individual and society. It is an indicator of one of the leading health problems in the world and it is outcome measure in clinical trials, observational studies and quality assurance programs. These studies and programs require a precise and consistent definition of myocardial infraction.

Additionally, the management of patients with myocardial infraction has significantly improved, resulting in less myocardial injury and necrosis, in spite of a similar clinical presentation. Moreover, it appears necessary to distinguish the various conditions which may cause myocardial infraction such as spontaneous and procedure-related myocardial infraction. Accordingly, physicians, other healthcare providers and patients require an up-to-date definition of myocardial infraction.